Genomic Variation Lab  

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ECL 290 Winter 2007

Instructors: Holly Ernest, Bernie May and John Eadie



course objectives (pdf)

software websites (pdf)

course questions (pdf)

Week 1:  Introduction to different types of markers Josh Hull, Molly Stephens, and Rachel Schwartz

AFLP powerpoint (pdf) Molly Stephens

Microsatellite data and analysis (pdf) Josh Hull

Week 2:  Review of key population genetic concepts Ann T. Chang, Elizabeth Long, Adam Wentzell, and Jennifer Kurushima

Handout on key population genetic concepts (pdf) Elizabeth Long

Fstats powerpoint (pdf) Elizabeth Long

Hardy-Weinberg and linkage disequilibrium powerpoint (pdf) Ann Chang

Notes of frequentist, maximum likelihood, and Bayesian statistics (pdf) Jessica Petersen

Allele numbers and frequencies powerpoint (pdf) Jennifer Kurushima

Genetic Distance powerpoint (pdf) Adam Wentzell

Week 3:  Getting Started with a data set

(Part 1) Renate Eberl and Lindsay Clark

Using NTSYS-pc for Principal Coordinate Analysis of dominant data (pdf) Molly Stephens

Whichloci powerpoint (pdf) Lindsay Clark

Whichloci handout (pdf) Lindsay Clark

Microsatellite toolkit and CONVERT handout (pdf) Renate Eberl

getting started with a data set powerpoint (pdf) Renate Eberl

Week 4: Getting started with a data set: Genepop on the Web and GDA

(Part 2) Rachel Simmons and Mandi Finger

Robertson, Alan and Hill, William G. 1984.  Deviations from Hardy-Weinberg proportions: sampling variances and use in estimation of inbreeding coefficients.  Genetics 107:703-718.

GDA user's guide (pdf)

Weir, B.S. and C. Clark Cockerham 1984. Estimating F-statistics for the Analysis of Population Structure.  Evolution 38:1358-1370.

Rice, William R. 1989. Analyzing Tables of Statistical Tests. Evolution 43:223-225.

Week 5: Getting started with the data set: Genepop on the Web and Fstat

(Part 3) Andrea Drauch and Joana Fernandes

Genepop and Fstat handout (pdf) Andrea Drauch

Week 6: Using STRUCTURE Kraig Kraft and Sarah Brown, Jason Sexton

STRUCTURE handout (pdf)

STRUCTURE powerpoint (pdf)

Choosing a K:

log likelihood (pdf)

delta K and Evano's ad hoc statistic (pdf)

Testing STRUCTURE with complex population structures using simulated data handout (pdf)

EASYPOP software:

Week 7: GENETIX  Ann T. Chang, Philip Lavretsky, and Annabelle Kleist

GENETIX handout (pdf)

GENETIX powerpoint (pdf)

Using FCA (Factorial Correspondence Analysis) powerpoint (pdf) Annabelle Kleist

Week 8: Geneclass and Assignment testing

Geneclass and assignment testing powerpoint (pdf) Catarina Ginja

Assignment testing applications (and misapplications) powerpoint (pdf) Catarina Ginja

Week 9: Kinship analysis and relatedness Jennifer Kurushima, Beverly Ajie

Relatedness powerpoint (pdf)

SPAGeDi handout (pdf)

ML-Relate handout (pdf)

K-coefficients handout (pdf)

Week 10: Parentage analysis Mariah Meek and Jessica Petersen

Parentage analysis powerpoint (pdf) Mariah Meek and Jessica Petersen

CERVUS powerpoint (pdf) Mariah Meek

Comparison between CERVUS and ML-Relate powerpoint (pdf) Jessica Petersen

CERVUS handout (pdf)